A Medical Breakthrough: Dendritic Cell Immunotherapy

Medical science and industry is an ever growing area. Immunotherapy, which has already been awarded a Nobel Prize, is one of the fastest growing areas in oncology. It could one day help doctors cure even the most advanced cancers. One method of immunotherapy is the use of dendritic cell vaccines. This type of vaccine for cancer treatment is made individually for a particular patient. Dendritic cells are taken from a person, activated, and then injected into the body to stimulate antitumor immunity. Their use is promising in many types of cancer, for example, dendritic cells immunotherapy for prostate cancer has been shown to improve overall life expectancy.

How Does Dendritic Cell Therapy Work?

Dendritic cells are a type of white blood cell whose main function is to present cancer antigens to T-cells (killers of malignant cells). Without dendritic cells, T-cells do not work because they are not able to recognize the antigen.

Dendritic cells facilitate the interaction of innate and adaptive immune responses. They have the unique ability to transport tumor antigens to the lymph nodes and trigger T-cell activation. This is an important process that is necessary for the functioning of T-cell-dependent immunity.

Dendritic cell deficiency has been shown to be present in many types of malignant disease. This type of immunotherapy therefore targets the cause of the cancer.

When Are Dendritic Cell Basis Vaccines Used?

Vaccination is a growing field in oncology, and most cancer vaccines are still in clinical trials. Sipuleucel-T was the first approved vaccine with proven efficacy and safety. It is made individually from the patient’s dendritic cells, which are activated by prostate acid phosphatase. The vaccine increases the life expectancy of patients with advanced prostate cancer.

However, most dendritic cell vaccines against cancer are still being researched. Promising results have already been obtained in the treatment of the following diseases:

  • Glioblastoma
  • Breast, ovarian, pancreatic cancers
  • Melanoma
  • Soft tissue and bone sarcomas
  • Central nervous system tumors
  • Colorectal cancer

Vaccines are used both in monotherapy and in combination with other cancer treatments. They are used mainly in the advanced stages of pathology, as well as in case of recurrence of a malignant tumor.

How to Have Your Dendritic Cell Vaccine

Dendritic cell vaccines are usually a part of a comprehensive cancer treatment. They also show good results when used in combination with other methods of immunotherapy treatment. For example, trials have shown an increase in the life expectancy in patients with melanoma and pancreatic cancer when a vaccine is added to the treatment regimen.

Germany offers dendritic cell vaccines to foreign patients who can’t or don’t want to be treated in their own country. If you want to undergo dendritic cell immunotherapy, you can use the Booking Health service. Here you can find the best German clinic to start your treatment and learn about dendritic cell immunotherapy costs.